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Lipopolysaccharide kinase (Kdo/WaaP) family

In molecular biology, the lipopolysaccharide kinase family is a family of kinases. The family consists of lipopolysaccharide kinases, including lipopolysaccharide core heptoseI kinase rfaP encoded by the gene waaP rfaP). Lipopolysaccharide core h ...

Lon protease family

In molecular biology, the Lon protease family is a family of proteases. They are found in archaea, bacteria and eukaryotes. Lon proteases are ATP-dependent serine peptidases belonging to the MEROPS peptidase family S16. In the eukaryotes the majo ...

LSm

In molecular biology, LSm proteins are a family of RNA-binding proteins found in virtually every cellular organism. LSm is a contraction of like Sm, because the first identified members of the LSm protein family were the Sm proteins. LSm proteins ...

LY6

LY6 also known as lymphocyte antigen 6 or urokinase-type plasminogen activator receptor is family of proteins that share a common structure but differ in their tissue expression patterns and function. Ly6 are cysteine-rich proteins that form disu ...

LydA holin family

The LydA Holin Family, named after the lydA gene which codes for its prototype member, belongs to the Holin Superfamily III. Members of this family have 3 transmembrane segments and appear to possess between 90 and 120 amino acyl residues. A repr ...

Lysine exporter

Lysine Exporters are a superfamily of transmembrane proteins which export amino acids, lipids and heavy metal ions. They provide ionic homeostasis, play a role in cell envelope assembly, and protect from excessive concentrations of heavy metals i ...

M2 hol family

The Mycobacterial 2 TMS Phage Holin Family is a group of transporters belonging to the Holin Superfamily VII. The Mycobactrerial 2 transmembrane segment Holins have been identified and recognized by Catalao et al. The Mycobacterium phage D29 gp11 ...

Magnesium transporter E

Magnesium transporters E are a family of transmembrane eubacterial MgtE magnesium transporters. Related regions are found also in archaeal and eukaryotic proteins. They have sizes that vary considerably from 311 residues for the Methanococcus the ...

Manganese exporter

The Manganese Exporter Family is a member of the Lysine Exporter Superfamily. The MntP family is a small family whose members have been found in bacteria and archaea. MntP proteins are of about 200 amino acyl residues with 6 putative transmembran ...

MED6

Mediator of RNA polymerase II transcription subunit 6 is one of the subunits of the Mediator complex. It is an enzyme that in humans is encoded by the MED6 gene.

MED27

Mediator of RNA polymerase II transcription subunit 27 is an enzyme that in humans is encoded by the MED27 gene. It forms part of the Mediator complex. The ubiquitous expression of Med27 mRNA suggests a universal requirement for Med27 in the init ...

MED28

Mediator of RNA polymerase II transcription subunit 28 is an enzyme that in humans is encoded by the MED28 gene. It forms part of the Mediator complex.

MED29

Mediator of RNA polymerase II transcription subunit 29 is a transcription suppressor that in humans is encoded by the MED29 gene. It represents subunit MED29 of the Mediator complex. Med29, along with Med11 and Med28 in mammals, is part of the co ...

MED31

Mediator of RNA polymerase II transcription subunit 31 is a protein in humans encoded by the MED31 gene. It represents subunit Med31 of the Mediator complex. The family contains the Saccharomyces cerevisiae SOH1 homologues. SOH1 is responsible fo ...

Mercury transporter

The mercury transporter superfamily is a family of transmembrane bacterial transporters of mercury ions. The common origin of all Mer superfamily members has been established. The common elements between family members are included in TMSs 1-2. A ...

Metalloproteinase

A metalloproteinase, or metalloprotease, is any protease enzyme whose catalytic mechanism involves a metal. An example of this would be ADAM12 which plays a significant role in the fusion of muscle cells during embryo development, in a process kn ...

Mitochondrial carrier

Mitochondrial carriers are proteins from a solute carrier family which transfer molecules across the membranes of the mitochondria. Mitochondrial carriers are also classified in the Transporter Classification Database. The Mitochondrial Carrier S ...

Mitochondrial ribosomal death-associated protein 3

In molecular biology, the mitochondrial ribosomal death-associated protein 3 family of proteins is a family of conserved proteins which were originally described as death-associated-protein-3. The proteins carry a P-loop DNA-binding motif, and in ...

MOP flippase

The multidrug/oligosaccharidyl-lipid/polysaccharide flippase superfamily is a group of integral membrane protein families. The MOP flippase superfamily includes twelve distantly related families, six for which functional data are available: One A ...

MP4 holin family

The Mycobacterial 4 TMS Phage Holin Family is a group of transporters belonging to Holin superfamily IV. A representative list of members belonging to the MP4 holin family can be found in the Transporter Classification Database. A member of the m ...

Multi-antimicrobial extrusion protein

M ulti- a n t imicrobial e xtrusion protein also known as multidrug and toxin extrusion or multidrug and toxic compound extrusion is a family of proteins which function as drug/sodium or proton antiporters.

Myogenic determination factor 5

In molecular biology, the myogenic determination factor 5 proteins are a family of proteins found in eukaryotes. This family includes the Myf5 protein, which is responsible for directing cells to the skeletal myocyte lineage during development. M ...

N-glycosyltransferase

N -glycosyltransferase is an enzyme in prokaryotes which transfers individual hexoses onto asparagine sidechains in substrate proteins, using a nucleotide-bound intermediary, within the cytoplasm. They are distinct from regular N -glycosylating e ...

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7

In molecular biology, the NADH dehydrogenase 1 alpha subcomplex subunit 7 family of proteins form a part of NADH dehydrogenase. In mammals, it is encoded by the NDUFA7 gene.

Notch proteins

Notch proteins are a family of type-1 transmembrane proteins that form a core component of the Notch signaling pathway, which is highly conserved in metazoans. The Notch extracellular domain mediates interactions with DSL family ligands, allowing ...

Nucleoporin

Nucleoporins are a family of proteins which are the constituent building blocks of the nuclear pore complex. The nuclear pore complex is a massive structure embedded in the nuclear envelope at sites where the inner and outer nuclear membranes fus ...

Octamer transcription factor

Octamer transcription factors are a family of transcription factors which binds to the "ATTTGCAT" DNA sequence. Their DNA-binding domain is a POU domain. There are eight Octamer of proteins in the human Oct1–11, which was renamed in accordance wi ...

Octopine dehydrogenase family

In molecular biology, the octopine dehydrogenase family of enzymes act on the CH-NH substrate bond using NAD or NADP as an acceptor. The family includes octopine dehydrogenase EC 1.5.1.11, nopaline dehydrogenase EC 1.5.1.19, lysopine dehydrogenas ...

OGFr

Opioid growth factor receptor, also known as OGFr or the ζ-opioid receptor, is a protein which in humans is encoded by the OGFR gene. The protein encoded by this gene is a receptor for opioid growth factor, also known as -enkephalin. The endogeno ...

Olfactory marker protein

In molecular biology, olfactory marker protein is a protein involved in signal transduction. It is a highly expressed, cytoplasmic protein found in mature olfactory sensory receptor neurons of all vertebrates. OMP is a modulator of the olfactory ...

Oligogalacturonate-specific porin

Oligogalacturonate-specific porins are a family of outer bacterial membrane proteins from Dickeya dadantii. The phytopathogenic Gram-negative bacteria D. dadantii secretes pectinases, which are able to degrade the pectic polymers of plant cell wa ...

Oligosaccaryltransferase

In molecular biology, OST4 is a subunit of the oligosaccharyltransferase complex. OST4 is a very short, approximately 30 amino acids, protein found from fungi to vertebrates. It appears to be an integral membrane protein that mediates the en bloc ...

OmpA domain

In molecular biology, the OmpA domain is a conserved protein domain with a beta/alpha/beta/alpha-beta structure found in the C-terminal region of many Gram-negative bacterial outer membrane proteins, such as porin-like integral membrane proteins, ...

Ornatin

In molecular biology, ornatin is a potent glycoprotein IIb-IIIa antagonist and platelet aggregation inhibitor isolated from Placobdella ornata. The protein is 41-52 amino acids in length and contains the RGD recognition motif common in adhesion p ...

OSTM1

Osteopetrosis-associated transmembrane protein 1 is a protein that in humans is encoded by the OSTM1 gene. It is required for osteoclast and melanocyte maturation and function.

Otopetrin family

The otopetrin family is a group of proteins that were first identified based on their essential role in the vestibular system, and were later shown to be expressed in many different tissues, including taste receptor cells. They are named after th ...

Outer membrane porin D

Outer membrane porin D is a protein family containing bacterial outer membrane porins which are involved in transport of cationic amino acids, peptides, antibiotics and other compounds. It was also described as having some serine protease activit ...

Oxaloacetate decarboxylase

Oxaloacetate decarboxylase is a carboxy-lyase involved in the conversion of oxaloacetate into pyruvate. It is classified under EC 4.1.1.3. In some bacteria, this enzyme is a trimer, composed of alpha -, beta-and gamma-subunits. Beta-and gamma-sub ...

Oxoguanine glycosylase

8-Oxoguanine glycosylase also known as OGG1 is a DNA glycosylase enzyme that, in humans, is encoded by the OGG1 gene. It is involved in base excision repair. It is found in bacterial, archaeal and eukaryotic species.

P21 holin family

The Phage 21 S Family is a member of the Holin Superfamily II. P21 bacteriophage lysis protein s of choline TC# 1.E.1.1.1 is the prototype for class II holins. Lysis proteins have two transmembrane segments of the Tmss with the n - and C-Termini ...

P35 holin family

The PRD1 Phage P35 Holin Family is a member of Holin Superfamily III. The prototype for this family is the lipid-containing PRD1 enterobacterial phage holin protein P35 encoded by gene XXXV. It is a component of a typical holin-endolysin system w ...

Pacifastin

Pacifastin is a family of serine proteinase inhibitors found in arthropods. Pacifastin inhibits the serine peptidases trypsin and chymotrypsin. All pacifastin members that have been characterized at the molecular level are precursor peptides cons ...

Paraoxonase

Paraoxonases are a family of mammalian enzymes with aryldialkylphosphatase activity. There are three paraoxonase isozymes, which were originally discovered for their involvement in the hydrolysis of organophosphates. Studies have shown that the e ...

Peptide transporter carbon starvation family

The Peptide Transporter Carbon Starvation Family is a member of the APC superfamily and consists of proteins from bacteria and archaea. These proteins are of various sizes and topologies. For example, CstA of E. coli has 701 aas with 18 putative ...

Phage major coat protein

In molecular biology, a phage major coat protein is an alpha-helical protein that forms a viral envelope of filamentous bacteriophages. These bacteriophages are flexible rods, about one to two micrometres long and six nm in diameter, with a helic ...

Phi11 holin family

The Phi11 Holin Family constitutes the Holin Superfamily I. One characterized member of this family, pneumococcal EJ-1 phage Holin Ejh, maybe# 1.E.11.1.3, represents a hydrophobic peptide of 85 amino acyl residues in length AAS 2 anticipated tran ...

Phi29 holin family

The Bacillus subtilis φ29 Holin Family is a group of transporters belonging to the Holin Superfamily IV. A representative list of members belonging to the φ29 holin family can be found in the Transporter Classification Database. Phage φ29 gene en ...

Pho1 family

The Pho1 phosphate permease family is a family of phosphate transporters belonging to the ion transporter superfamily. Representative members of the Pho1 family include the putative phosphate transporter PHO1 of Arabidopsis thaliana, and the xeno ...

Phosphate permease

Phosphate permeases are membrane transport proteins that facilitate the diffusion of phosphate into and out of a cell or organelle. Some of these families include: TC# 2.A.47.2 - Phosphate porters of the Divalent Anion:Na + Symporter DASS Family, ...

Phosphate-selective porin

Phosphate-selective porins are a family of outer bacterial membrane proteins. These are anion-specific porins, the binding site of which has a higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates, whi ...